Juan Francisco de la Serna Rosete
- Born: 21 Aug 1809, Cap. Fed., Arg.
- Christened: 22 Aug 1809, Buenos Aires, Distrito Federal, Argentina
- Marriage: Rosa Seferina Trias Cabral on 5 Oct 1852 in San Fernando, Bs. As., ARG
- Died: 3 Jun 1880, Montevideo, Uruguay at age 70
Juan married Rosa Seferina Trias Cabral, daughter of Pedro José Trias and Juana María Cabral, on 5 Oct 1852 in San Fernando, Bs. As., ARG. (Rosa Seferina Trias Cabral was born in Argentina and died on 5 May 1903 in La Plata, Bs As, Arg.)